How Curcumin Relieves PCOS and Inflammatory Diseases

Curcumin

How It Relieves PCOS and Inflammatory Diseases

Benefits of turmeric compound curcumin are too good to be true, but it is true. Find how it helps PCOS, inflammation, digestion, and learn how to take it.

These days, we take a rest in the rush. We often forget to realize that the Mother Nature has bestowed us with many wonderful herbs. In fact, many of them are in your kitchen. Regrettably, we turn to the natural remedies only after the modern medicines fail to meet our expectations. Ever thought turmeric could be your friend in alleviating PCOS symptoms? Did you know taking it regularly could save you from inflammatory diseases like arthritis? Maybe or maybe not. In any case, you should understand that several scientific studies back the health benefits of curcumin, the active chemical in turmeric.

A Quick Overview of Curcumin
Curcumin, the yellow compound present in turmeric, is a powerful polyphenol. It has anti-inflammatory, antioxidant and anticancer properties. People around the world have been using it to treat digestive disorders for decades. Moreover, it also influences your immune function. Thus, it may be a great treatment option for autoimmune disorders.

Exploring The Healing Power of Curcumin For Inflammation

Autophagy is actually the key to slow aging process. This can be achieved if you will restrict protein intake for a whole day. Protein fast can actually provide you several health benefits such as anti-aging and weight loss. Consuming a very little amount of protein and carbohydrates which is fewer than 15 grams fro a 24-hour period will train your body to look for other means to recycle proteins.

In short, indulging to “self-cannibalism,” it actually clears the clutter in your body which eventually makes you feel and look younger.  Your fats cells are consumed also which hastens your body to loss fats. Remember, that when your body is deficient in protein for a period of 24-hour, insulin levels are actually low which means your body won’t be able to store fat from the food that you eat.

Hence, health experts suggest that for a 24-hour period, it is recommended only that you consume fats and low-glycemic carbs.  In addition, it is also recommended that you eat fats and carbs in afternoon and night.

The importance of autophagy to maintain healthy cells was eloquently explained by Juleen Zierath, a member of the Nobel committee, who talked about Ohsumi’s discovery.

“Every day we need to replace about 200-300g of protein in our bodies. Every two to three months, every protein in our body turns over. Because of autophagy, these 200-300g of proteins are made. We are eating proteins every day, about 70g, but that’s not enough to take care of the requirement to make new proteins. Because of this machinery, we’re able to rely on some of our own proteins, maybe the damaged proteins or the long-lived proteins, and they are recycled with this sophisticated machinery so that we can sustain and we survive.”

It is now an established fact that cells use autophagy to remove damaged proteins and organelles, you body mechanism that counteract the negative consequences of aging.  Recently, there has been ongoing research to produce drugs that can target autophagy to cure different diseases such as Parkinson’s disease, type 2 diabetes, cancer and other disorders linked to disruptive autophagy.

How Curcumin Helps To Reduce Inflammation At Cellular Level

Curcumin is shown to relieve inflammation by one or more of the following mechanisms.

  • Blocking the release of the chemicals that signal inflammation.
  • Lowering cellular response by reducing the number of the chemical-binding sites (receptors) in the cells.
  • Preventing the accumulation of inflammatory cells like white blood cells in different regions including the brain.

Curcumin For PCOS: What You Should Know

PCOS (Polycystic Ovary Syndrome), the most common cause of female infertility, is a disorder of hormone imbalance. Women with PCOS, mostly in their reproductive years, have high levels of a male hormone testosterone. Missed or irregular periods, excessive body and facial hair and very high blood glucose levels are its common signs and symptoms.

A 2016 study involving rats found that curcumin is as effective as clomiphene citrate in treating PCOS. The possible mechanisms for the improvement in symptoms are given below.

  • It reduces the blood levels of testosterone by a huge margin. In addition, it causes a significant increase in the level of a female hormone estradiol.
  • A marked reduction in the blood levels of glucose and fats including bad cholesterol.
  • An increase in the levels of protective antioxidant enzymes like catalase, glutathione and superoxide dismutase.

Taking Curcumin To Aid Digestion: A New Look at the Age-old Practice

Interestingly, our ancestors seem to be wiser than us. At least, when we know the use of curcumin for digestive disorders dates back to centuries. Maybe we are a bit late to capture the subtle health effects of a turmeric-rich diet. Nonetheless, the modern science has started evaluating its effects on digestive disorders. And, the results are encouraging. Here some recent study results.

Curcumin is a potent anti-ulcer agent.

Know The Mechanism Behind

  • Because of its antioxidant and anti-inflammatory properties, curcumin protects the cells that line the digestive tract from gastric acid.
  • It helps to restore the tissues damaged by H.pylori, the bacteria responsible for gastric ulcers. In addition, it can also help to clear the bacteria from the stomach.
  • Ulcers due to a prolonged use of pain medications may also improve after curcumin therapy.

Curcumin could be a choice of alternative remedy for Crohn’s disease (CD), Ulcerative colitis (UC) and Irritable Bowel Syndrome (IBS).

Know The Mechanism Behind
CD and UC are collectively known as inflammatory bowel diseases (IBD). They occur when the immune cells attack the tissues in the digestive tract. Since curcumin has an anti-inflammatory property, it can cause a reduction in the severity of the symptoms. For example, diarrhea and abdominal cramps.

IBS is a well-known condition but only a little is known about its causes. However, the scientists suggest it might occur when the brain sends abnormal signals to the intestines. Also, they believe brain chemicals called neurotransmitters play a major role in the disease progression.

Curcumin can help the brain regulate the neurotransmitter levels and thus provide relief in IBS.

Is It Safe To Take Curcumin?
That’s a very good question and the answer is yes without a hint of doubt. When you take curcumin by mouth or apply its preparation topically, it is totally safe. Taking up to 8000 mg of curcumin per day for 3 months is shown to have no toxic effects in the human studies.

How To Take Curcumin For Better Results?

No doubt, getting your dose of curcumin from the diet is the best way to take it. However, it might not always be possible owing to the type of the diet and your changing needs.

If you are considering to supplement, make sure to buy the supplement from reputable sellers only. Also, read the labels carefully before taking it. Note the amount of curcumin present in each dose and other ingredients in the preparation. The dose can vary depending on the type of preparation.

Most experts recommend taking a curcumin supplement (400mg-800mg) on an empty stomach. That is at least 30 minutes before a meal. However, if this causes heartburn or upset stomach, you could take it two hours after a meal.

IMPORTANT: If you are taking other medicines, pregnant or trying to get pregnant, consult your doctor before taking a curcumin supplement.

References

  1. Chainani-Wu Nita. “Safety and anti-inflammatory activity of curcumin: a component of turmeric (Curcuma longa).” Journal of Alternative and Complementary Medicine 2003 Feb;9(1):161-8.
  2. Li, Jian., et al. “Curcumin protects endothelial cells against homocysteine induced injury through inhibiting inflammation.” American Journal of Translational Research 2016 Nov 15;8(11):4598-4604.
  3. Gupta, Subash C., et al. “Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials” Then AAPS Journal 2013 Jan; 15(1): 195–218.
  4. Liu, Wei., et al. “Curcumin reduces brain-infiltrating T lymphocytes after intracerebral hemorrhage in mice.” Neuroscience Letters 2016 May 4;620:74-82.
  5. Dulbecco. Pietro., et al. “Therapeutic potential of curcumin in digestive diseases” World Journal of Gastroenterology 2013 Dec 28; 19(48): 9256–9270.
  6. Reddy, Sushma P., et al. “Beneficial effect of Curcumin in Letrozole induced polycystic ovary syndrome” Asian Pacific Journal of Reproduction Volume 5, Issue 2, April 2016, Pages 116-122.
  7. Yadav, Santosh Kumar., et al. “Turmeric (curcumin) remedies gastroprotective action” Pharmacognosy Review 2013 Jan-Jun; 7(13): 42–46.
  8. Taylor, Rebecca A., et al. “Curcumin for inflammatory bowel disease: a review of human studies.” Alternative Medicine Review 2011 Jun;16(2):152-6.

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